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Experience has indicated depakote for dementia treatment children under the age of two years are at a considerably increased risk of developing fatal hepatotoxicity.especially those with the aforementioned conditions. When Depakote ER is used in this patient group.it should be used with extreme caution and as a sole agent. The benefits of therapy should be weighed against the risks. In progressively older patient groups experience in epilepsy has indicated that the incidence of fatal hepatotoxicity decreases considerably.

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Do not use in women of childbearing age unless the drug is essential to the management of the medical condition. all non-pregnant women of childbearing potential should use effective birth control if taking valproate products (see Contraindications and Pregnancy sections) May cause neural tube defects Children exposed in utero have increased risk for lower cognitive test scores compared with those exposed in utero to other antiseizure medications Alternative medications that have a lower risk for adverse birth outcomes should be considered Patients should not stop taking valproate without talking to a health-care professional Women should use effective contraception while taking valproate derivatives.

Depakote ER initial dose. 25 mg/kg PO once daily Increase as rapidly as possible to achieve the lowest therapeutic dose that provides desired clinical effect or plasma concentration.

References. 1. Depakote [package insert]. North Chicago.IL. AbbVie Inc. 2. Depakote ER [package insert]. North Chicago.IL. AbbVie Inc. 3. Depakote Sprinkle Capsules [package insert]. North Chicago.IL. AbbVie Inc.

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Taking Depakote during pregnancy can harm your unborn babyincreasing the risk of serious birth defectse.gbrainspinal cordspina bifidaheartheadarmslegs and penisand the risk of your child having a lower IQCall your doctor if you are pregnant or become pregnant.

What is DepakoteDepakote is a medication known as an anticonvulsant that is used to treat the manic symptoms of bipolar disorderIt is also used to treat seizures and prevent migraine headaches.

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