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SKIN AND SKIN STRUCTURE INFECTIONS caused by Bacteroides species including the Bfragilis groupClostridium speciesPeptococcus speciesPeptostreptococcus speciesand Fusobacterium species.
FLAGYL is indicated in the treatment of acute intestinal amebiasisamebic dysenteryand amebic liver abscess.
Anaerobic InfectionsTreatment of infections in which anaerobic bacteria have been identified or are suspected as pathogensparticularly Bacteroides fragilis and other species of bacteroidesand other species such as fusobacteriaeubacteriaclostridia and anaerobic streptococciFlagyl has been used successfully in septicaemiabacteraemiabrain abscessnecrotising pneumoniaosteomyelitispuerperal sepsispelvic abscesspelvic cellulitispostoperative wound infectionsNoteMetronidazole is inactive against aerobic and facultative anaerobic bacteriaOther IndicationsOral treatment of urogenital trichomoniasis in the femaletrichomonal vaginitisand in the maleand for the treatment of bacterial vaginosisThe male consort of females suffering from urogenital trichomoniasis should be treated concurrentlyall forms of amoebiasisintestinal and extraintestinal disease and that of symptomless cyst passersgiardiasisacute ulcerative gingivitis.
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Disposition of metronidazole in the body is similar for both oral and intravenous dosage formsFollowing oral administrationmetronidazole is well absorbedwith peak plasma concentrations occurring between one and two hours after administration.
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