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Drug prolongs QT interval and may lead to sudden death. Don’cheap procardia give to patients with hypokalemia.hypomagnesemia.or long-QT syndrome. Correct hypokalemia or hypomagnesemia before starting drug and monitor for these imbalances periodically. Avoid concomitant drugs known to prolong QT interval. also avoid strong CYP3A4 inhibitors. Instruct patient not to eat 2 hours before or 1 hour after taking dose. Obtain ECG to monitor QTc at baseline.7 days after drug initiation.periodically thereafter.and after dosage adjustments.
There have been rare reports of increased prothrombin time cheap procardia patients taking coumarin anticoagulants to whom Procardia was administered. However.the relationship to Procardia therapy is uncertain.
This is not a complete list of possible side effects. If you notice other effects not listed above.contact your doctor or pharmacist.
See adult dosage. In general.initiate dosage at the lower end of the adult dosage range. Nifedipine plasma concentrations and half-life are significantly increased in geriatric patients. Adjust dosage based on clinical response.
You may need to take an extended-release tablet on an empty stomach. Follow the directions on your medicine label about taking this medication with or without food.
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Swallow wholeDo not chewbreakor crushTo gain the most benefitdo not miss dosesKeep taking Procardianifedipine capsulesas you have been told by your doctor or other health care providereven if you feel wellDo not stop taking Procardianifedipine capsulesall of a sudden without calling your doctorYou may have a greater risk of side effectsIf you need to stop Procardianifedipine capsulesyou will want to slowly stop it as ordered by your doctor.
This is not a list of all drugs or health problems that interact with Procardianifedipine capsules
Althoughlike other members of its classProcardia decreases sinoatrial node function and atrioventricular conduction in isolated myocardial preparationssuch effects have not been seen in studies in intact animals or in manIn formal electrophysiologic studiespredominantly in patients with normal conduction systemsProcardia has had no tendency to prolong atrioventricular conductionprolong sinus node recovery timeor slow sinus rate.
This drug may make you dizzyAlcohol or marijuana can make you more dizzyDo not driveuse machineryor do anything that needs alertness until you can do it safelyLimit alcoholic beveragesTalk to your doctor if you are using marijuana.
Rarelypatientsusually receiving a beta blockerhave developed heart failure after beginning ProcardiaPatients with tight aortic stenosis may be at greater risk for such an eventas the unloading effect of Procardia would be expected to be of less benefit to these patientsowing to their fixed impedance to flow across the aortic valve.
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Tell your doctor and pharmacist about all of your drugsprescription or OTCnatural productsvitaminsand health problemsYou must check to make sure that it is safe for you to take Procardianifedipine capsuleswith all of your drugs and health problemsDo not startstopor change the dose of any drug without checking with your doctor.
Swallow wholeDo not chewbreakor crushTo gain the most benefitdo not miss dosesKeep taking Procardianifedipine capsulesas you have been told by your doctor or other health care providereven if you feel wellDo not stop taking Procardianifedipine capsulesall of a sudden without calling your doctorYou may have a greater risk of side effectsIf you need to stop Procardianifedipine capsulesyou will want to slowly stop it as ordered by your doctor.
(See INDICATIONS AND USAGE and WARNINGSExperience in over 1400 patients in a non-comparative clinical trial has shown that concomitant administration of Procardia and beta-blocking agents is usually well toleratedbut there have been occasional literature reports suggesting that the combination may increase the likelihood of congestive heart failuresevere hypotension or exacerbation of angina.
Overdose symptoms may include severe dizzinesspounding heartbeatsnauseavomitingand feeling like you might pass out.
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Barbiturates eg, phenobarbital , carbamazepine, or rifampin because they may decrease procardia s effectiveness beta-blockers eg, propranolol , cimetidine, cyclosporine, fluconazole, fluoxetine, imatinib, itraconazole, ketanserin, magnesium salts eg, injectable magnesium sulfate , quinazolines eg, metolazone , quinidine, or ranitidine because side effects, including very low blood pressure, may occur beta-blockers eg, propranolol , cyclosporine, digoxin, hydantoins eg, phenytoin , ketanserin, lithium, theophylline, vinca alkaloids eg, vincristine because the actions and side effects of these medicines may be increased quinidine, theophylline, or vinca alkaloids eg, vincristine because their effectiveness may be decreased by procardia.
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Store at room temperatureProtect from lightStore in a dry placeDo not store in a bathroomKeep all drugs in a safe placeKeep all drugs out of the reach of children and petsThrow away unused or expired drugsDo not flush down a toilet or pour down a drain unless you are told to do soCheck with your pharmacist if you have questions about the best way to throw out drugsThere may be drug take-back programs in your area.
Procardia dilates the main coronary arteries and coronary arteriolesboth in normal and ischemic regionsand is a potent inhibitor of coronary artery spasmwhether spontaneous or ergonovine-inducedThis property increases myocardial oxygen delivery in patients with coronary artery spasmand is responsible for the effectiveness of Procardia in vasospasticPrinzmetal’s or variantanginaWhether this effect plays any role in classical angina is not clearbut studies of exercise tolerance have not shown an increase in the maximum exercise rate-pressure producta widely accepted measure of oxygen utilizationThis suggests thatin generalrelief of spasm or dilation of coronary arteries is not an important factor in classical angina.
If you are also taking a beta-blockersuch as BetapaceCoregCorgardDutoprolInderalInnoPranLopressorNormodyneTenorminTenoreticToprolTrandateand othersdo not suddenly stop using the beta blocker without first talking to your doctorYou may need to use less and less before you stop the medication completelyStopping a beta blocker too quickly can cause serious heart problems that will not be prevented by nifedipine.
An empty tablet shell may appear in your stoolThis is harmless since your body has already absorbed the medication.
Several well-controlledrandomized trials studied the use of immediate-release nifedipine in patients who had just sustained myocardial infarctionsIn none of these trials did immediate-release nifedipine appear to provide any benefitIn some of the trialspatients who received immediate-release nifedipine had significantly worse outcomes than patients who received placeboProcardia capsules should not be administered within the first week or two after myocardial infarctionand they should also be avoided in the setting of acute coronary syndromewhen infarction may be imminent
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