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Frequency not reported . False-positive Benedict’s tests (due to an unknown reducing substance) [Ref]

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When determining the LD 50 in rats and miceprogressive sedationhypnosisand finally respiratory failure were noted as the dosage increasedIn dogsno LD 50 could be determined as the higher doses produced an emetic action in 15 to 30 minutes.

Although plasma protein binding and absolute bioavailability of metaxalone are not knownthe apparent volume of distributionV/F.

Chemicallymetaxalone is 53,5dimethylphenoxymethyl2-oxazolidinoneThe empirical formula is C 12 H 15 NO 3which corresponds to a molecular weight of 221.25The structural formula is:

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