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Clinical trials of several COX-2 selective and nonselective NSAIDs of up to three years duration have shown an increased risk of serious cardiovascular (CV) thrombotic events.myocardial infarction.and stroke.which can be fatal. All NSAIDs.both COX-2 selective and nonselective.may have a similar risk. Patients with known CV disease or risk factors for CV disease may be at greater risk. Buy toradol pills minimize the potential risk for an adverse CV event in patients treated with an NSAID.the lowest effective dose should be used for the shortest duration possible. Physicians and patients should remain alert for the development of such events.even in the absence of previous CV symptoms. Patients should be informed about the signs and/or symptoms of serious CV events and the steps to take if they occur.

The effects of warfarin and NSAIDs.in general.on GI bleeding are synergistic.such that the users of both drugs together have a risk of serious GI bleeding higher than the users of either drug alone.

In postmarketing experience there have been reports of a possible interaction between ketorolac tromethamine IV/IM and nondepolarizing muscle relaxants that resulted in apnea. The concurrent buy toradol pills of ketorolac tromethamine with muscle relaxants has not been formally studied.

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